Of course, you need a big, ultimate goal to shoot for. It helps to not think in terms of "I want to weigh this much" but rather "I want to be able to do one-armed pushups" or "I want to run ten miles". Once you figure out the goal, then you find out the steps you need to get there.
Let's say you want to do one-arm pushups, but you can't even do one regular one right now. Start with wall pushups. When you can do 50 of those, 3 times over, then do pushups against a table or a chair. When you can do 50 of those, 3 times over, then do pushups from your knees. When you can do 40 of those, 3 times over, then go to regular pushups. When you can do 20 of those, 3 times over, then move your hands close together. Then put one hand on a basketball. Eventually, you'll be able to do one-handed pushups.
Personally, I would stay away from pills. They can damage your health, they're expensive, and once you start taking them the weight just comes right back. You're better off changing the way you eat. The first step is to track what you're eating right now. Sites like fitday.com let you enter what you eat and give you a breakdown of how much fat, protein and carbohydrate you're consuming. When you have that, you can start making changes.
Simple rules for eating: if it comes in a box, bag, or can, don't eat it. The exception to this rule is frozen vegetables or fruit. Eat lean protein, vegetables, fruit, and whole grains. Don't eat white sugar, white potatoes, white bread, or white noodles. Brown rice, oatmeal, quinoa, and wholegrain bread that doubles as a doorstop are your friends. Read food labels. You have to change the way you think about food; if you approach this as just a way to lose weight, you'll fail, and you'll beat yourself up for failing. If you approach this as a way to make yourself as healthy as possible, you'll do much better.
DO NOT starve yourself! If you try to live on 1000 calories a day, your brain won't work and you won't lose weight. Your body will just shut down.
You might want to head over to nerdfitness.com; it's a fitness and weight-loss community for non-athletes. There's lots of great resources and information, and the folks are friendly.
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